Who Needs LDN (Low Dose Naltrexone)?

Question: Do you know of any contradictions with LDN that would affect liver enzymes?  I take both LDN and Copaxone and also drink wine daily.  My wife noticed some yellowing in the whites of my eyes.  I always understood that the 4.5 mg dose was too small to do any liver damage.

Answer: Naltrexone is potentially harmful to the liver. It is commonly thought to be related to the daily dose. However, that may not always be the case. Some people are much more susceptible to substances that are toxic to the liver. No dose is ever “too small” to cause harm. While it is unlikely that 4.5mg can be dangerous, it is still very possible.

Question: Is it safe to take vicodin while taking 3mg naltrexone?  I have managed to fracture my right arm and was prescribed vicodin for pain at the hospital.  They were aware of my taking naltrexone daily but only had knowledge of the 50 mg dose.The drug label says hydrocodone/apap 5/500 tab generic for vicodin 5/500 tablet.

Answer: LDN is NOT to be used when any opioid is being used.
Vicodin is a potent opioid.
The dose is not as important as one might think.
We’ve heard of serious problems arising even when the 3.0mg is use at the same time as an opioid.

Short and simple: if you use opioids, don’t use LDN. If you use LDN, don’t use opioids.

The following is taken from TheCompounder.com/msnaltrexone.php

Cautionary warnings: Because naltrexone blocks opioid receptors throughout the body for several hours, people using narcotic medication (such as codeine or morphine) should not take naltrexone simultaneously. It should probably not be taken during pregnancy.

Full-dose naltrexone (50mg) carries a cautionary warning against its use in those with liver disease. This warning was placed because of adverse liver effects that were found in experiments involving 300mg daily. The 50mg dose does not apparently produce impairment of liver function nor, of course, does the much smaller 3mg dose.

Welcome!

WhoneedsLDN.com hopes to give some light into the real life questions of people researching, taking or thinking about taking low dose naltrexone or being treated for multiple sclerosis, lymes disease, irritable bowel syndrome, or any of the autoimmune disease and are looking for something else.

If you ever have any questions, my contact info is below and we welcome any and all comments!

Larry J. Frieders, RPh
larry @ thecompounder.com  http://www.thecompounder.com
340 Marshall, Unit 100 ~ Aurora, IL 60506  Tel 630-859-0333
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